樊良鑫 副教授
办公室：文化路校区18号楼307
Email：fanlx@henau.edu.cn；fannwu@yeah.net
电话：15891766015（微信同号）
主讲课程
研究生：学位课《有机化学专题》、选修课《杂原子化学》
本科生：《有机化学》、《普通化学》、《环境化学》、《基础化学实验 I-II》
研究领域与兴趣
金属催化化学
有机合成方法学
药物中间体合成
教育背景
2014.09-2019.06 西北大学化学与材料科学学院 有机化学 理学博士（硕博连读）
2010.09-2014.07 兰州城市学院化学化工学院 化学 理学学士
工作履历
2024.02-至今 河南农业大学 副教授 硕士生导师
2019.12-2024.01 河南农业大学 讲师（校聘教授） 硕士生导师
学术兼职和社会兼职
中国化学会会员、中国化工学会会员
奖励与荣誉
2023 年河南农业大学“挑战杯”大学生课外学术科技作品竞赛三等奖指导教师
2023 年河南农业大学优秀教师
2023 年河南农业大学“优秀抗疫青年志愿者”
2022 年河南省优秀学士学位论文（毕业设计）指导教师
2022 届河南农业大学本科毕业论文（设计）优秀指导教师
2022 年河南农业大学青年教师课堂教学技能竞赛二等奖
2022 年河南农业大学疫情防控优秀志愿者
2021 年陕西省优秀博士学位论文（全省 100 篇）
2020 年度陕西高等学校科学技术奖一等奖
2019 年西北大学优秀博士学位论文、2019 届西北大学优秀毕业生
科研项目
主持国家自然科学基金青年项目—基于酰胺键断裂的 DNQ 型卡宾前体的创制及其应用研究 2024.01-2026.12，30 万，在研
主持河南农业大学拔尖人才项目—基于惰性化学键活化的氮杂环分子合成反应研究 2012.12-2024.12，140 万，在研
指导2023 年国家级大学生创新训练项目—新型氟代喹啉类杀菌剂的设计、绿色合成及其应 用研究，2023.12-2024.12，0.5 万，在研
主持河南省自然科学基金青年项目—基于碳氮键活化的吲唑酮化合物及其类似物合成研究， 2022.01-2023.07，5 万，结项
主持河南省高等学校重点科研项目—基于碳氮键活化的吲唑酮化合物及其类似物合成研究， 2021.01-2022.12，3 万，结项
参与河南省科技攻关项目—基于亚丙二烯金属中间体的不对称炔丙基化反应的协同催化体 系开发，2021.01-2023.07，结项
参与河南省自然科学基金面上项目—可再生资源木质素中关键化学键还原羰化断裂的研究， 2021.01-2023.12，10 万，结项
参与河南省科技攻关项目—生物质炭化木头的金属整体电极对生物高分子的电催化分解， 2022.01-2024.07，在研
参与国家自然科学基金面上项目—过渡金属催化碳氢键活化/去芳构化的协同反应策略研究， 2017.01-2020.03，65 万，结项
参与河南省农业领域科技攻关项目—具有杀菌活性的新型含氟香豆素衍生物的分子设计、合 成与应用研究，2019.01-2021.06，10 万，结项
参与河南省科技攻关项目—绕丹宁类药物分子制备新方法的研究与应用，2023.01-2024.12， 在研
参与河南省烟草公司平顶山市公司科技项目—烟草除草剂安全剂的开发与应用研究， 2022.01-2024.12，50 万，在研 参与元素有机化学国家重点实验室（南开大学）开放基金项目—过渡金属 催化碳氢键活化/ 去芳构化的螺环化反应研究，2016.01-2017.12，3 万，结项
学术成果
[1] Jiang Nan*; Haiyan Xiao; Yangmin Ma; Liangxin Fan*; Jing Wang*, Palladium-Catalyzed Domino Conversion of Aryl-Thianthreniumswith Anhydrides: Rapidly Building Highly FunctionalizedFluorenones, Org. Lett. 2024, 26(16), 3332–3337.
[2] Liangxin Fan # ; Jiamao Hao # ; Jingxu Yu; Xiaojun Ma; Jingjing Liu; Xinjun Luan*, Hydroxylamines As Bifunctional Single-Nitrogen Sources for the Rapid Assembly of Diverse Tricyclic Indole Scaffolds, J. Am. Chem. Soc. 2020, 142, 6698.
[3] Liangxin Fan # ; Jingjing Liu # ; Lu Bai; Yaoyu Wang; Xinjun Luan*; Rapid Assembly of Diversely Functionalized Spiroindenes by a Three-Component Palladium-Catalyzed C-H Amination/Phenol Dearomatization Domino Reaction, Angew. Chem. Int. Ed. 2017, 56, 14257.
[4] Liangxin Fan*, Mengyang He, Xingyuan Liu, Fangyu He, Lulu Wu, Guoyu Yang, Zhenliang Pan, Lijun Shi, Caixia Wang, Cuilian Xu*, Direct access to carbamates via acylation of arylamines with dialkyl azodicarboxylates under metal-free conditions, Org. Biomol. Chem., 2023, 21, 9037.
[5] Liangxin Fan*, Fangyu He, Lijun Shi, Guoyu Yang, Zhenliang Pan, Miaomiao Wang, Caixia Wang, Lulu Wu, Senyu Han, Yifang Guo, Cuilian Xu*, Green synthesis of 2-trifluoromethyl quinoline derivatives under metal-free conditions and their antifungal properties, J. Saudi Chem. Soc., 2023, 27, 101621.
[6] Liangxin Fan*, Xinxin Zhu, Xingyuan Liu, Fangyu He, Guoyu Yang, Cuilian Xu*, Xifa Yang*, Recent Advances in the Synthesis of 3,n-Fused Tricyclic Indole Skeletons via Palladium Catalyzed Domino Reactions, Molecules, 2023, 28, 1647.
[7] Lulu Wu; Xinxin Yuan; Guoyu Yang; Cuilian Xu; Zhenliang Pan; Lijun Shi; Caixia Wang; Liangxin Fan*, An eco-friendly procedure for the synthesis of new phosphates using KF/Al2O3 under solventless conditions and their antifungal properties, J. Saudi Chem. Soc., 2021, 25, 101273.
[8] Xifa Yang,* Song Li, Yuhao He, Danhua Dai, Mengyao Bao, Ziyang Luo, Xiangyang Liu, Yuehua Geng, and Liangxin Fan*, Rhodium(III)-catalyzed oxidative cross-coupling of benzoxazinones with styrenes via C–H activation, Org. Biomol. Chem., 2023, 21, 797.
[9] Liangxin Fan, Fangyu He, Lijun Shi, Xiao Li, Cuilain Xu*, Progress in Syntheses of Indazolones, Chemistry, 2022, 85, 1077.
[10] Bingyi Zhou, Guoyu Yang, Caixia Wang, Lijie Liu, Lijun Shi, Zhenliang Pan, Xiaoming Ji,* Lulu Wu, Huayu Zheng, Cuilian Xu,* and Liangxin Fan*; Highly Chemoselective Synthesis of Azaarene-Equipped CF3-TertiaryAlcohols under Metal-Free Conditions and Their Fungicidal Activities, ACS omega, 2022, 7, 38084.
[11] Zhijun Zuo # , Hui Wang # , Liangxin Fan; Jingjing Liu; Yaoyu Wang; Xinjun Luan*; Modular Assembly of Spirocarbocyclic Scaffolds through Pd 0 -Catalyzed Intermolecular Dearomatizing [2+2+1] Annulation of Bromonaphthols with Aryl Iodides and Alkynes, Angew. Chem. Int. Ed. 2017, 56, 2767.
[12] Zhijun Zuo; Jingjing Liu; Jiang Nan; Liangxin Fan; Wei Sun; Yaoyu Wang; Xinjun Luan*; Highly Stereoselective Synthesis of Imine-Containing Dibenzo[b,d]azepines by a Palladium(II)-Catalyzed [5+2] Oxidative Annulation of o-Arylanilines with Alkyne, Angew. Chem. Int. Ed. 2015, 54, 15385.
[13] Xiaodan Chang, Liangxin Fan, Lijun Shi, Zhenliang Pan, Guoyu Yang, Cuilian Xu*, Lulu Wu*, Caixia Wang, Catalyst- and solvent-free coupling of 2-methylquinazolinones and 3-(trifluoroacetyl)coumarins: An environmentally benign access of quinazolinone derivatives, J. Saudi Chem. Soc., 2023, 27, 101621.
[14] Caixia Wang, Liangxin Fan , Zhenliang Pan, Sufang Fan, Lijun Shi, Xu Li, Jinfang Zhao, Lulu Wu, Guoyu Yang* and Cuilian Xu*, Synthesis of Novel Indole Schiff Base Compounds and Their Antifungal Activities, Molecules, 2022, 27, 6858.
[15] Lulu Wu, Zhenliang Pan, Liangxin Fan, Guoyu Yang, Lijun Shi, Shengfei Jiang, Xiaodan Chang, Bingyi Zhou, Yanyan Yang, Cuilian Xu*, Caixia Wang*, A one-pot approach to novel α-trifluoromethylated coumarin-bearing tertiary alcohols promoted by CH3COOH/NH4OAc via consecutive ring-opening/aldol sequence, J. Saudi Chem. Soc., 2023, 27, 101578.
[16] Bingyi Zhou, Xinxin Yuan, Liangxin Fan, Zhenliang Pan, Xiaodan Chang, Shengfei Jiang, Lulu Wu, Caixia Wang, Guoyu Yang, Xiaoming Ji*, Lijun Shi*, Cuilian Xu*, Synthesis and antifungal activities of novel trifluoroethane derivatives with coumarin, indole and thiophene, J. Saudi Chem. Soc., 2022, 26, 101572.
[17] Lijie Liu, §* Jinjin Wang, § Xingxiao Wang, Haoran Wang, Mengzhen Li, Tongyuan Wu, Guangqin Gao, Xin Zheng, Guoxing Liu, Liangxin Fan, Wenbo Shen, Guangxin Ru,* Zheng Zhao,* and Ben Zhong Tang*. High-Resolution Imaging of Latent Fingerprints Through Near-Infrared Organoboron AIEgens, Chin. J. Chem., 2023. 10.1002/cjoc.202200677.
[18] Shengfei Jiang, Guoyu Yang, Lijun Shi, Liangxin Fan, Zhenliang Pan, Caixia Wang, Xiaodan Chang, Bingyi Zhou, Meng Xu, Lulu Wu,* and Cuilian Xu*, Design, Catalyst-Free Synthesis of New Novel α-Trifluoromethylated Tertiary Alcohols Bearing Coumarins as Potential Antifungal Agents, Molecules, 2023, 28, 260.
[19] Guangqin Gao, Jinjin Wang, Xingxiao Wang, Guoxing Liu, Liangxin Fan, Guangxin Ru, Shun Wang, Meirong Song, Wenbo Shen, Xin Zheng, Lei Han, and Lijie Liu*, Reversible Near-Infrared Fluorescent Probe for Rapid Sensing Sulfur Dioxide and Formaldehyde: Recognition and Photoactivation Mechanism and Applications in Bioimaging and Encryption Ink, Anal. Chem., 2022, 94, 13590.
[20] Wan-Kai An*, Shi-Jia Zheng, Xin Xu, Li-Jie Liu, Jia-Sen Ren, Liangxin Fan, Zhan-Kun Yang, Yunlai Ren*, Cuilian Xu, Integrating benzofuran and heteroradialene into donor-acceptor covalent organic frameworks for photocatalytic construction of multi-substituted olefins, Appl. Catal. B-Environ., 2022, 316, 121630.
[21] Jingjing Zhang; Mengying Zhang; Mingxin Lu; Yuhao He; Song Li; Liangxin Fan; Xinle Zhang; Jia-Kai Wu; Xifa Yang*; Synthesis of spiropyrans via the Rh(III)-catalyzed annulation of 3-aryl-2H-benzo[b][1,4]oxazines with diazo ketoesters, Chem. Commun., 2022, 58, 5144.
[22] Guoyu Yang; Lijun Shi; Zhenliang Pan; Lulu Wu; Liangxin Fan; Caixia Wang; Cuilian Xu*; Jun Liang, The synthesis of coumarin thiazoles containing a triflfluoromethyl group and their antifungal activities, Arab. J. Chem., 2021, 14, 102880.
[23] Zhenliang Pan, Wankai An, Lulu Wu, Liangxin Fan, Guoyu Yang, Cuilian Xu, A New Synthesis Strategy for Rhodanine and Its Derivatives, Synlett, 2021, 32, 1131.
[24] Chengyong Gao, Hua Wang, Huirong Zhao, Sheng Shi, Hong Guo, Shuhua Wang, Liangxin Fan, Study on the quality and inkjet printing effect of the prepared washing-free disperse dye ink, RSC Adv., 2023, 13, 12141.
[25] 樊良鑫，李晓，郑先福，孟磊。高等农林院校“普通化学”课程教学现阶段现状及改革 探索，广东化工，2021，48，299.
[26] 史力军, 姚晨, 杨国玉, 樊良鑫, 王彩霞, 徐翠莲, 常见有机化合物中文词汇的读音详解, 化学教育, 2023, 44, 21.
[27] 樊良鑫，杨西发，徐翠莲等。一种苯胺类化合物酰基化方法，发明专利，专利号：ZL 202210081775.0
[28] 樊良鑫，何方雨，徐翠莲等。一种 2-三氟甲基喹啉类化合物及其合成方法和应用，发 明专利，专利号：ZL 202211320692.9
[29] 徐翠莲，樊良鑫，姬小明等。一种三氟甲基叔醇及其合成方法和应用，发明专利，专利号：ZL 202210763073,0
[1] Jiang Nan*; Haiyan Xiao; Yangmin Ma; Liangxin Fan*; Jing Wang*, Palladium-Catalyzed Domino Conversion of Aryl-Thianthreniumswith Anhydrides: Rapidly Building Highly FunctionalizedFluorenones, Org. Lett. 2024, 26(16), 3332–3337.
[2] Liangxin Fan # ; Jiamao Hao # ; Jingxu Yu; Xiaojun Ma; Jingjing Liu; Xinjun Luan*, Hydroxylamines As Bifunctional Single-Nitrogen Sources for the Rapid Assembly of Diverse Tricyclic Indole Scaffolds, J. Am. Chem. Soc. 2020, 142, 6698.
[3] Liangxin Fan # ; Jingjing Liu # ; Lu Bai; Yaoyu Wang; Xinjun Luan*; Rapid Assembly of Diversely Functionalized Spiroindenes by a Three-Component Palladium-Catalyzed C-H Amination/Phenol Dearomatization Domino Reaction, Angew. Chem. Int. Ed. 2017, 56, 14257.
[4] Liangxin Fan*, Mengyang He, Xingyuan Liu, Fangyu He, Lulu Wu, Guoyu Yang, Zhenliang Pan, Lijun Shi, Caixia Wang, Cuilian Xu*, Direct access to carbamates via acylation of arylamines with dialkyl azodicarboxylates under metal-free conditions, Org. Biomol. Chem., 2023, 21, 9037.
[5] Liangxin Fan*, Fangyu He, Lijun Shi, Guoyu Yang, Zhenliang Pan, Miaomiao Wang, Caixia Wang, Lulu Wu, Senyu Han, Yifang Guo, Cuilian Xu*, Green synthesis of 2-trifluoromethyl quinoline derivatives under metal-free conditions and their antifungal properties, J. Saudi Chem. Soc., 2023, 27, 101621.
[6] Liangxin Fan*, Xinxin Zhu, Xingyuan Liu, Fangyu He, Guoyu Yang, Cuilian Xu*, Xifa Yang*, Recent Advances in the Synthesis of 3,n-Fused Tricyclic Indole Skeletons via Palladium Catalyzed Domino Reactions, Molecules, 2023, 28, 1647.
[7] Lulu Wu; Xinxin Yuan; Guoyu Yang; Cuilian Xu; Zhenliang Pan; Lijun Shi; Caixia Wang; Liangxin Fan*, An eco-friendly procedure for the synthesis of new phosphates using KF/Al2O3 under solventless conditions and their antifungal properties, J. Saudi Chem. Soc., 2021, 25, 101273.
[8] Xifa Yang,* Song Li, Yuhao He, Danhua Dai, Mengyao Bao, Ziyang Luo, Xiangyang Liu, Yuehua Geng, and Liangxin Fan*, Rhodium(III)-catalyzed oxidative cross-coupling of benzoxazinones with styrenes via C–H activation, Org. Biomol. Chem., 2023, 21, 797.
[9] Liangxin Fan, Fangyu He, Lijun Shi, Xiao Li, Cuilain Xu*, Progress in Syntheses of Indazolones, Chemistry, 2022, 85, 1077.
[10] Bingyi Zhou, Guoyu Yang, Caixia Wang, Lijie Liu, Lijun Shi, Zhenliang Pan, Xiaoming Ji,* Lulu Wu, Huayu Zheng, Cuilian Xu,* and Liangxin Fan*; Highly Chemoselective Synthesis of Azaarene-Equipped CF3-TertiaryAlcohols under Metal-Free Conditions and Their Fungicidal Activities, ACS omega, 2022, 7, 38084.
[11] Zhijun Zuo # , Hui Wang # , Liangxin Fan; Jingjing Liu; Yaoyu Wang; Xinjun Luan*; Modular Assembly of Spirocarbocyclic Scaffolds through Pd 0 -Catalyzed Intermolecular Dearomatizing [2+2+1] Annulation of Bromonaphthols with Aryl Iodides and Alkynes, Angew. Chem. Int. Ed. 2017, 56, 2767.
[12] Zhijun Zuo; Jingjing Liu; Jiang Nan; Liangxin Fan; Wei Sun; Yaoyu Wang; Xinjun Luan*; Highly Stereoselective Synthesis of Imine-Containing Dibenzo[b,d]azepines by a Palladium(II)-Catalyzed [5+2] Oxidative Annulation of o-Arylanilines with Alkyne, Angew. Chem. Int. Ed. 2015, 54, 15385.
[13] Xiaodan Chang, Liangxin Fan, Lijun Shi, Zhenliang Pan, Guoyu Yang, Cuilian Xu*, Lulu Wu*, Caixia Wang, Catalyst- and solvent-free coupling of 2-methylquinazolinones and 3-(trifluoroacetyl)coumarins: An environmentally benign access of quinazolinone derivatives, J. Saudi Chem. Soc., 2023, 27, 101621.
[14] Caixia Wang, Liangxin Fan , Zhenliang Pan, Sufang Fan, Lijun Shi, Xu Li, Jinfang Zhao, Lulu Wu, Guoyu Yang* and Cuilian Xu*, Synthesis of Novel Indole Schiff Base Compounds and Their Antifungal Activities, Molecules, 2022, 27, 6858.
[15] Lulu Wu, Zhenliang Pan, Liangxin Fan, Guoyu Yang, Lijun Shi, Shengfei Jiang, Xiaodan Chang, Bingyi Zhou, Yanyan Yang, Cuilian Xu*, Caixia Wang*, A one-pot approach to novel α-trifluoromethylated coumarin-bearing tertiary alcohols promoted by CH3COOH/NH4OAc via consecutive ring-opening/aldol sequence, J. Saudi Chem. Soc., 2023, 27, 101578.
[16] Bingyi Zhou, Xinxin Yuan, Liangxin Fan, Zhenliang Pan, Xiaodan Chang, Shengfei Jiang, Lulu Wu, Caixia Wang, Guoyu Yang, Xiaoming Ji*, Lijun Shi*, Cuilian Xu*, Synthesis and antifungal activities of novel trifluoroethane derivatives with coumarin, indole and thiophene, J. Saudi Chem. Soc., 2022, 26, 101572.
[17] Lijie Liu, §* Jinjin Wang, § Xingxiao Wang, Haoran Wang, Mengzhen Li, Tongyuan Wu, Guangqin Gao, Xin Zheng, Guoxing Liu, Liangxin Fan, Wenbo Shen, Guangxin Ru,* Zheng Zhao,* and Ben Zhong Tang*. High-Resolution Imaging of Latent Fingerprints Through Near-Infrared Organoboron AIEgens, Chin. J. Chem., 2023. 10.1002/cjoc.202200677.
[18] Shengfei Jiang, Guoyu Yang, Lijun Shi, Liangxin Fan, Zhenliang Pan, Caixia Wang, Xiaodan Chang, Bingyi Zhou, Meng Xu, Lulu Wu,* and Cuilian Xu*, Design, Catalyst-Free Synthesis of New Novel α-Trifluoromethylated Tertiary Alcohols Bearing Coumarins as Potential Antifungal Agents, Molecules, 2023, 28, 260.
[19] Guangqin Gao, Jinjin Wang, Xingxiao Wang, Guoxing Liu, Liangxin Fan, Guangxin Ru, Shun Wang, Meirong Song, Wenbo Shen, Xin Zheng, Lei Han, and Lijie Liu*, Reversible Near-Infrared Fluorescent Probe for Rapid Sensing Sulfur Dioxide and Formaldehyde: Recognition and Photoactivation Mechanism and Applications in Bioimaging and Encryption Ink, Anal. Chem., 2022, 94, 13590.
[20] Wan-Kai An*, Shi-Jia Zheng, Xin Xu, Li-Jie Liu, Jia-Sen Ren, Liangxin Fan, Zhan-Kun Yang, Yunlai Ren*, Cuilian Xu, Integrating benzofuran and heteroradialene into donor-acceptor covalent organic frameworks for photocatalytic construction of multi-substituted olefins, Appl. Catal. B-Environ., 2022, 316, 121630.
[21] Jingjing Zhang; Mengying Zhang; Mingxin Lu; Yuhao He; Song Li; Liangxin Fan; Xinle Zhang; Jia-Kai Wu; Xifa Yang*; Synthesis of spiropyrans via the Rh(III)-catalyzed annulation of 3-aryl-2H-benzo[b][1,4]oxazines with diazo ketoesters, Chem. Commun., 2022, 58, 5144.
[22] Guoyu Yang; Lijun Shi; Zhenliang Pan; Lulu Wu; Liangxin Fan; Caixia Wang; Cuilian Xu*; Jun Liang, The synthesis of coumarin thiazoles containing a triflfluoromethyl group and their antifungal activities, Arab. J. Chem., 2021, 14, 102880.
[23] Zhenliang Pan, Wankai An, Lulu Wu, Liangxin Fan, Guoyu Yang, Cuilian Xu, A New Synthesis Strategy for Rhodanine and Its Derivatives, Synlett, 2021, 32, 1131.
[24] Chengyong Gao, Hua Wang, Huirong Zhao, Sheng Shi, Hong Guo, Shuhua Wang, Liangxin Fan, Study on the quality and inkjet printing effect of the prepared washing-free disperse dye ink, RSC Adv., 2023, 13, 12141.
[25] 樊良鑫，李晓，郑先福，孟磊。高等农林院校“普通化学”课程教学现阶段现状及改革 探索，广东化工，2021，48，299.
[26] 史力军, 姚晨, 杨国玉, 樊良鑫, 王彩霞, 徐翠莲, 常见有机化合物中文词汇的读音详解, 化学教育, 2023, 44, 21.
[27] 樊良鑫，杨西发，徐翠莲等。一种苯胺类化合物酰基化方法，发明专利，专利号：ZL 202210081775.0
[28] 樊良鑫，何方雨，徐翠莲等。一种 2-三氟甲基喹啉类化合物及其合成方法和应用，发 明专利，专利号：ZL 202211320692.9
[29] 徐翠莲，樊良鑫，姬小明等。一种三氟甲基叔醇及其合成方法和应用，发明专利，专利号：ZL 202210763073,0